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Mitochondrial Link to Cerebellar Decline in MS

Neuroscience News - 16 Jun 2025 21:34
Mitochondrial Link to Cerebellar Decline in MS A new study reveals that mitochondrial dysfunction plays a central role in the loss of Purkinje neurons in the cerebellum, contributing to motor impairments in people with multiple sclerosis (MS). Researchers found that inflammation and demyelination in the cerebellum disrupt the mitochondria--key cellular power sources--leading to energy loss, neuron damage, and ataxia.
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